Scientist / Senior Scientist, LNP Formulation & Process Development

We're hiring at Deep Piction

Deep Piction is a Munich-based biotechnology company developing advanced drug-delivery, whole-body imaging, spatial biology, and AI technologies to accelerate therapeutic development.

We are looking for a Scientist – LNP Formulation & Preclinical Development (m/f/d) to join our nanotechnology team and support the development of LipiGO, our targeted lipid nanoparticle platform for therapeutic RNA delivery.

About the role

This is a hands-on laboratory position for someone who enjoys designing experiments, formulating LNPs, troubleshooting, and working closely with biology and pharmacology teams to advance RNA therapeutics from concept to in vivo validation.

You will contribute directly to formulation development while helping coordinate internal and external preclinical studies in a dynamic biotechnology environment.

Your responsibilities

LNP formulation & characterization

• Prepare and optimize lipid nanoparticle formulations for mRNA delivery

• Characterize LNPs using DLS and related analytical methods

• Perform formulation optimization, stability testing, and troubleshooting

• Produce reproducible LNP batches for in vitro and in vivo studies

• Document formulation procedures, experimental results, and SOPs

Preclinical development

• Plan and coordinate internal in vitro and in vivo pharmacology studies

• Design and monitor external studies with academic collaborators, CROs, and industry partners

• Coordinate external safety and toxicology studies

• Support assay development for formulation characterization and biological evaluation

• Analyze experimental data and prepare scientific reports

Project coordination

• Write and review preclinical study reports

• Contribute to EIC, KMU, and other grant reports

• Support regulatory documentation and non-clinical development activities

• Establish and maintain organized data rooms for partners, investors, and regulatory interactions

• Implement structured data documentation and file-management systems

• Coordinate activities across the internal development pipeline

What we're looking for

• MSc or PhD in biotechnology, pharmaceutical sciences, chemistry, biomedical engineering, nanomedicine, or a related field

• Strong hands-on experience with lipid nanoparticles or other nucleic-acid delivery systems

• Experience with LNP formulation, bioconjugation techniques, and physicochemical characterization

• Experience with mRNA, siRNA, or oligonucleotide formulations

• Experience with techniques such as DLS, RiboGreen assays, gel electrophoresis, or comparable methods

• Ability to plan experiments independently and troubleshoot technical problems

• Strong organizational skills and the ability to coordinate multiple projects simultaneously

• Excellent written and spoken English

Strong advantages

• Experience with ligand-conjugated LNPs

• Experience with flow cytometry and in vitro LNP performance studies

• Experience supporting animal studies or managing external CROs

• Experience writing scientific or grant reports

• Knowledge of preclinical development and regulatory documentation

• A strong interest in translating research into therapeutic applications

What we offer

• A hands-on role developing next-generation RNA therapeutics

• Direct involvement in formulation development from bench to preclinical validation

• Work across nanotechnology, biology, imaging, AI, and drug development

• Close collaboration with leading academic and industrial partners

• A collaborative and interdisciplinary team based in Munich

• Competitive compensation based on experience

• Flexible start date

Application process

Please submit your application as one single PDF containing:

• Your CV

• A cover letter explaining why you are a strong fit for the position

• A clear description of your relevant experience in LNP formulation, characterization, preclinical studies, and project coordination

• What expertise and practical capabilities you would bring to Deep Piction

Please do not attach certificates, references, recommendation letters, publication PDFs, or other supporting documents at this stage.

Important: Only applications sent to [email protected] as one single PDF containing the CV and cover letter will be evaluated. Applications submitted through LinkedIn or other channels will not be considered.

Send your application to:

[email protected]

Required email subject:

Scientist – LNP Formulation & Preclinical Development (DP-LNP-2026-01)

• Applications will be reviewed on a rolling basis until the position is filled.

Standort

Deep Piction, Munich